Spiramycin is a macrolide antibiotic used primarily to treat toxoplasmosis in pregnant women to prevent transmission to the fetus. It also treats various bacterial infections, including respiratory tract infections (bronchitis, sinusitis), skin infections, and dental infections. It is also used for cryptosporidiosis and certain sexually transmitted infections. Mayo Clinic +4 Key Uses of Spiramycin Toxoplasmosis in Pregnancy: The drug of choice to reduce the risk of transmitting Toxoplasma gondii from a pregnant mother to the fetus. Dental Infections: Commonly used to treat acute odontostomatological infections (infections in the mouth). Respiratory Tract Infections: Used for treating infections such as acute sinusitis, bronchitis, and pharyngitis. Skin and Soft Tissue Infections: Effective for infections like cellulitis and impetigo. Other Infections: Used for treating gonorrhea (in penicillin-allergic patients) and as an off-label or investigative treatment for Cryptosporidium diarrhea in immunocompromised patients.